• Intra Uterine Insemination (IUI)
IUI should be performed in cases where the woman has healthy fallopian tubes and the sperm parameters are satisfactory. IUI involves the injection of prepared sperm from the husband, partner or donor into the woman’s uterine cavity. It is generally a painless procedure which takes only a few minutes.
• In-vitro fertilization (IVF/ICSI)
In vitro Fertilisation is where fertilisation takes place in the laboratory and is the treatment used when the egg and sperm cannot come together in the normal way. Once the eggs have been collected they are mixed with sperm in dishes and cultured overnight. The day after their collection, all the eggs are examined and all normally fertilised eggs cultured for at least another 24hours before embryo transfer. The best quality embryos are selected by the embryologists for transfer.
In couples with poor sperm numbers or function, or with a previous failed cycle or low fertilisation rate, ICSI may be indicated. A single sperm is selected and injected into each of the eggs collected, using specialised equipment. Only embryologists who have been trained and licensed are permitted to carry out the procedure.
• Blastocyst transfer
In our unit we will often suggest to transfer blastocysts depending on the number and quality of embryos available three days after egg collection. This will help the laboratory team to select the best embryos for embryo transfer because there are a large number of rapidly developing, good quality embryos on day 3.
• Embryo Freezing
Embryos not transferred to the uterus may be suitable for freezing according to the wishes of the couple. We recommend freezing when there are good quality embryos left after the embryo transfer is completed. Poor quality embryos, or embryos which are slow to develop, are unlikely to survive freezing and thawing to give a reasonable chance of pregnancy
• Egg freezing
Egg freezing is an option to women who are facing a total loss of, or a significant decline in, ovarian function due to chemotherapy or age which may have an impact on their future fertility.
Vitrification is the latest freezing method and it offers excellent survival rates for embryo and eggs.
• Sperm Donation
Although we do not have a sperm donor bank here, we buy in sperm from two highly reputable and licensed centres in Europe and make every effort to find a suitable donor profile for each woman/couple.
• Egg Donation
All recipients and donors are carefully medically screened and meet with our counsellors to discuss ethical, emotional, social and legal implications of their decision.
The surrogacy option may offer many people a possibility for parenthood. The issues (psychological, ethical, moral and legal) all need careful consideration. Anyone considering surrogacy should explore all the options, obtain as much information as possible, and seek guidance from both counselors and specialists in choosing the best path to parenthood for you.
The surrogacy process may be considered by a Commissioning woman:
- who has functioning ovaries but no uterus
- who has reproductive tract malformations
- who is incapable of carrying a pregnancy for medical reasons
- who has had many unsuccessful attempts at IVF and embryo transfers
- who has history of repeated miscarriage
• Assisted Hatching
This technique involves using micromanipulation to thin or make a hole in the outside shell or zona pellucida of the embryo to help the embryo ‘hatch’ and subsequently implant. The evidence for improving pregnancy rates is not conclusive and again this technique should only usually be used in older patients or those with repeated IVF failure.
• Preimplantation genetic diagnosis(PGD)
Pre-Implantation Genetic Aneuploidy Screening aims to improve the chance of having a healthy live birth in the following patient groups:
- Women aged 40 and above
- Couples who have undergone at least three fresh IVF cycles without success
- Women who suffer from recurrent miscarriages.